Related Experiment Video
Updated: Sep 18, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
The changing incidence of acute pancreatitis in children: a single-institution perspective
1Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of Texas Southwestern Medical Center, Dallas, 73590-9063, USA.
Insights
Pediatric pancreatitis incidence rose between 1993-1998, but causes remained similar. Infants with pancreatitis often had multisystem illness, and idiopathic pancreatitis was rare in young children.
Area of Science:
- Pediatric Gastroenterology
- Clinical Epidemiology
Background:
- Pancreatitis in children is a significant clinical concern.
- Understanding trends and etiologies is crucial for pediatric healthcare.
Purpose of the Study:
- To analyze the etiologic factors and annual incidence of pediatric pancreatitis.
- To compare current findings with historical data.
Main Methods:
- Retrospective review of all pediatric pancreatitis cases from 1993 to 1998.
- Data collection on etiologic factors and case frequency.
Main Results:
- An increase in pancreatitis incidence was observed during the study period.
- The spectrum of etiologic factors remained consistent with previous reports.
- Pancreatitis in infants was frequently linked to multisystem diseases.
- Idiopathic pancreatitis was uncommon in children under six and absent in those under three.
Conclusions:
- Pediatric pancreatitis incidence is increasing, yet etiological factors are stable.
- Early-onset pancreatitis in infants is often a marker of broader systemic illness.
- Idiopathic pancreatitis is rare in very young children.
Abstract:
All cases of pancreatitis examined between 1993 and 1998 were reviewed to determine the etiologic factors and the number of cases per year. Although the incidence increased, the spectrum of etiologic factors did not differ greatly from those in previous series of pancreatitis in children. Pancreatitis in infants was associated with multisystem illness. Idiopathic pancreatitis was uncommon in children younger than 6 years of age and not observed in children younger than 3 years of age.
Related Concept Videos
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis I: Introduction
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology

