Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Mutations at Positions 181 and 185 Within the LCMV GP Protein Increase Tumor Cell Infectivity, Limit Induction of Type I Interferon, and Accelerate T Cell Activation.

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Lymphocytic Choriomeningitis Virus Bearing GPC Mutations for Enhanced Tumor Tropism and Strong Anti-Tumor Activity.

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Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties.

Cell reports. Medicine·2025

New insights into the role of IFN-α/β and TLR7/8/9 in cancer immunotherapy and systemic autoimmunity.

Journal for immunotherapy of cancer·2025

First-in-human study of an EGFRvIII x CD3 T cell bispecific antibody in the treatment of newly diagnosed glioblastoma.

Neuro-oncology advances·2025

Abundance, Diet and Foraging of Galápagos Barn Owls (Tyto furcata punctatissima).

Animals : an open access journal from MDPI·2025

Metastasis enables immunogenicity through migrasome-mediated antigen release.

Nature immunology·2026

Deletion of a distal IRF4 element prevents inflammation-induced reprogramming of human regulatory T cell fate.

Nature immunology·2026

Spatiotemporal single-cell profiling reveals T cell clonal dynamics and phenotypic plasticity in human graft-versus-host disease.

Nature immunology·2026

ANKRD11 deficiency reprograms CD8+ T cell differentiation to enhance immunity in chronic infection and cancer.

Nature immunology·2026

Microbial adhesion promotes Piezo1 activation to initiate innate immunity.

Nature immunology·2026

AMBRA1 allosterically activates NLRP3 by releasing its autoinhibition.

Nature immunology·2026

SMAS Plication Facelift and Platysmaplasty Under Tumescent Local Anesthesia: a 10-Year Retrospective Evaluation of Safety, Efficacy, and Patient Satisfaction in an Outpatient Setting.

Aesthetic plastic surgery·2026

Alternative splicing-dependent T218 phosphoregulation controls SR45.1 nuclear organization and salt stress responses in Arabidopsis.

Plant cell reports·2026

Statistical shape modeling for digital nasal prosthesis design: Subjective and anthropometric validation.

Journal of prosthodontics : official journal of the American College of Prosthodontists·2026

Sol-Gel Process Optimization of Transparent Silica Aerogels: Regulating Nanostructure to Enhance Optical Transmittance.

Nanomaterials (Basel, Switzerland)·2026

Satisfaction With Anaplastology and Willingness for Face Transplantation in Patients With Facial Epitheses: A Pretest Study.

The Journal of craniofacial surgery·2026

Theoretical investigation of an ultra-sensitive angular refractive index sensor based on compound parabolic micro-funnel arrays.

Optics letters·2026

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Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Related Concept Videos

Mutations at Positions 181 and 185 Within the LCMV GP Protein Increase Tumor Cell Infectivity, Limit Induction of Type I Interferon, and Accelerate T Cell Activation.

Lymphocytic Choriomeningitis Virus Bearing GPC Mutations for Enhanced Tumor Tropism and Strong Anti-Tumor Activity.

Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties.

New insights into the role of IFN-α/β and TLR7/8/9 in cancer immunotherapy and systemic autoimmunity.

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Abundance, Diet and Foraging of Galápagos Barn Owls (Tyto furcata punctatissima).

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Deletion of a distal IRF4 element prevents inflammation-induced reprogramming of human regulatory T cell fate.

Spatiotemporal single-cell profiling reveals T cell clonal dynamics and phenotypic plasticity in human graft-versus-host disease.

ANKRD11 deficiency reprograms CD8+ T cell differentiation to enhance immunity in chronic infection and cancer.

Microbial adhesion promotes Piezo1 activation to initiate innate immunity.

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SMAS Plication Facelift and Platysmaplasty Under Tumescent Local Anesthesia: a 10-Year Retrospective Evaluation of Safety, Efficacy, and Patient Satisfaction in an Outpatient Setting.

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