Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hohenheim consensus workshop: copper.

K Schümann1, H G Classen, H H Dieter

  • 1Walther-Straub-Institut für Pharmakologie und Toxikologie der LMU, München, Germany.

European Journal of Clinical Nutrition
|May 29, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Economic evaluation of the Very Early Rehabilitation in SpEech (VERSE) intervention.

Topics in stroke rehabilitation·2023
Same author

Clinical implantation of 92 VACStents in the upper gastrointestinal tract of 50 patients-applicability and safety analysis of an innovative endoscopic concept.

Frontiers in surgery·2023
Same author

The VACStent trial: combined treatment of esophageal leaks by covered stent and endoscopic vacuum therapy.

Surgical endoscopy·2023
Same author

Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains.

Scientific reports·2021
Same author

Biocompatible, hyperbranched nanocarriers for the transport and release of copper ions.

Journal of materials chemistry. B·2020
Same author

Application of Theory in Studies of Healthcare Built Environment Research.

HERD·2020

Dietary copper (Cu) is vital for enzymes but toxic in excess, potentially causing diseases. Research is needed to understand Cu homeostasis and identify at-risk groups, like infants, for better diagnostics.

Area of Science:

  • Biochemistry
  • Human Physiology
  • Toxicology

Background:

  • Copper (Cu) is an essential trace element crucial for numerous physiological functions, acting as a cofactor for enzymes involved in cellular defense.
  • Imbalances in copper homeostasis can lead to deficiency or toxic accumulation, contributing to hepatic, neurodegenerative, and cardiovascular diseases.

Framework:

  • This commentary explores the dual role of dietary copper, examining its essentiality in enzymatic processes and its toxicity.
  • The inherent physico-chemical properties of copper, particularly its ability to generate hydroxyl radicals via Fenton-like reactions, underlie its toxic potential.

Implementation:

  • Focuses on understanding the role of dietary copper supply in both deficiency and overload states.
  • Highlights the need to identify genetic predispositions for copper overload diseases and assess risk groups, such as infants with compromised copper detoxification mechanisms.

Related Experiment Videos

Implications:

  • Emphasizes the critical need for reliable diagnostic markers to accurately determine copper status in at-risk populations.
  • Calls for a re-assessment of existing data and further research to elucidate copper's complex role in health and disease.