Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A physical dosimetry intercomparison for BNCT.

Kent J Riley1, Peter J Binns, Dennis D Greenberg

  • 1Nuclear Reactor Laboratory, Massachusetts Institute of Technology, Cambridge 02139, USA.

Medical Physics
|May 30, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of TK1 targeting carboranyl thymidine analogs as potential delivery agents for neutron capture therapy of brain tumors.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2015
Same author

Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer.

Radiation oncology (London, England)·2012
Same author

Comparison of intracerebral delivery of carboplatin and photon irradiation with an optimized regimen for boron neutron capture therapy of the F98 rat glioma.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2011
Same author

A novel method of boron delivery using sodium iodide symporter for boron neutron capture therapy.

Journal of radiation research·2010
Same author

Convection enhanced delivery of carboranylporphyrins for neutron capture therapy of brain tumors.

Journal of neuro-oncology·2010
Same author

Convection enhanced delivery of boronated EGF as a molecular targeting agent for neutron capture therapy of brain tumors.

Journal of neuro-oncology·2009
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

Physical dosimetry methods at MIT and BMRR show good agreement for Boron Neutron Capture Therapy (BNCT) trials. This intercomparison ensures accurate retrospective analysis and comparability of BNCT treatment protocols.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Nuclear Medicine

Background:

  • Boron Neutron Capture Therapy (BNCT) relies on precise physical dosimetry for treatment efficacy.
  • Intercomparison of dosimetry methods is crucial for retrospective analysis and protocol standardization.

Purpose of the Study:

  • To intercompare physical dosimetry methods between MIT and BMRR for BNCT.
  • To enable retrospective analysis of BNCT trials and compare treatment protocols.

Main Methods:

  • Measurements performed at BMRR epithermal neutron beam facility using MIT procedures.
  • Thermal neutron flux determined via gold foil activation.
  • Photon and fast neutron absorbed dose rates assessed using ionization chambers.

Related Experiment Videos

Main Results:

  • Good agreement in thermal neutron flux depth profiles between MIT and BMRR (1.01+/-0.10 at 3.5 cm).
  • Favorable agreement in in-phantom photon depth dose component (0.89+/-0.12 at 3.5 cm).
  • In-air dose rate measurements agreed within experimental uncertainty.

Conclusions:

  • Confirms reproducibility and uniformity of dosimetry measurements between MIT and BMRR.
  • Provides essential physical data for comparing BNCT treatment protocols.
  • Supports accurate retrospective analysis of BNCT clinical trials.