Adherence to disease-modifying therapy in multiple sclerosis: Part I.

Area of Science:

• Neurology
• Behavioral Science

Background:

• Multiple sclerosis (MS) is a chronic, incurable neurological disease.
• New immunomodulating agents can reduce relapses and slow progression, but require patient adherence for efficacy.
• Patient adherence is hindered by MS unpredictability and treatment side effects.

Purpose of the Study:

• To explore challenges in multiple sclerosis treatment adherence.
• To propose the transtheoretical model of behavior change as a solution for improving adherence.
• To provide guidance for nurses in supporting patient adherence.

Main Methods:

• Literature review on MS treatment adherence challenges.
• Application of the transtheoretical model of behavior change to MS management.
• Discussion of nursing interventions based on the model.

Main Results:

• Treatment adherence in MS is complex and requires addressing patient "readiness for change."
• The transtheoretical model provides a framework for tailoring interventions to patient's current stage of change.
• Nurses can utilize this model to enhance patient acceptance and adherence to therapy.

Conclusions:

• Improving adherence to multiple sclerosis therapies is crucial for realizing treatment benefits.
• The transtheoretical model offers a valuable approach for nurses to support patients in chronic disease management.
• Tailoring interventions to individual patient readiness can significantly improve treatment outcomes in MS.