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Pituitary Adenomas.

Grant T. Liu1

  • 1Division of Neuro-ophthalmology, Department of Neurology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. gliu@mail.med.upenn.edu

Current Treatment Options in Neurology
|May 31, 2002
PubMed
Summary
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Pituitary adenoma treatment varies by type. Prolactinomas respond well to medication like bromocriptine or cabergoline, while other adenomas often require surgery. Prognosis for hormonal and vision recovery is generally favorable.

Area of Science:

  • Endocrinology
  • Neurosurgery
  • Oncology

Background:

  • Pituitary adenomas are tumors of the pituitary gland.
  • Treatment strategies depend on tumor type and symptoms.

Purpose of the Study:

  • To outline current treatment modalities for pituitary adenomas.
  • To discuss the efficacy of different therapeutic approaches.

Main Methods:

  • Review of pharmacologic treatments (bromocriptine, cabergoline) for prolactinomas.
  • Surgical intervention, primarily transsphenoidal surgery, for other symptomatic adenomas.
  • Role of radiation therapy as an adjunctive treatment.

Main Results:

  • Medical therapy is the primary approach for prolactinomas.

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  • Transsphenoidal surgery is standard for non-functioning or other symptomatic adenomas.
  • Radiation therapy is reserved for residual or recurrent tumors.

    • Conclusions:

    • Effective treatment options exist for pituitary adenomas.
    • Good prognosis for endocrinologic and visual outcomes is achievable with appropriate management.