Related Experiment Videos
A Pacinian corpuscle in the human bladder lamina propria.
1Department of Neuropathology, Institute of Neurology University College London and National Hospital for Neurology and Neurosurgery, UK. D.Landon@ion.ucl.ac.uk
Journal of Neurocytology
|May 31, 2002
Summary
Researchers discovered a complex Pacinian corpuscle in the human urinary bladder lining. This encapsulated nerve ending, found in the lamina propria, is the first reported instance in an adult bladder.
Area of Science:
- Urology
- Neuroanatomy
- Histology
Background:
- The human urinary bladder's sensory innervation is not fully understood.
- Pacinian corpuscles are mechanoreceptors typically found in deeper tissues.
Purpose of the Study:
- To describe the novel finding of a Pacinian corpuscle in the human urinary bladder.
- To characterize the structure and associations of this nerve ending.
Main Methods:
- Histological examination of human urinary bladder tissue.
- Microscopic analysis of encapsulated nerve structures.
Main Results:
- A complex Pacinian corpuscle was identified within the lamina propria, adjacent to the detrusor muscle.
- The corpuscle lacked structural evidence of directional sensitivity.
- Unmyelinated axons with vesicles were associated with the corpuscle's outer aspect.
Conclusions:
- This represents the first report of an encapsulated nerve ending, specifically a Pacinian corpuscle, in the adult human urinary bladder lining.
- The presence of this mechanoreceptor suggests potential roles in bladder sensation.