Related Experiment Video

Updated: Oct 1, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

[Neuromeningeal tuberculosis in northeastern suburbs of Paris. Nineteen cases]

Mylène Grimaud-Ayina1, Olivier Fain, Olivier Lortholary

  • 1Service de Médecine Interne, Laboratoire de Microbiologie, Hôpital Jean-Verdier, 93143 Bondy Cedex, France.

Annales De Medecine Interne
|May 31, 2002
PubMed
Abstract

Insights

Neuromeningeal tuberculosis predominantly affects young, foreign-born individuals and presents with non-specific symptoms. Delays in diagnosing this serious form of tuberculosis significantly impact patient outcomes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Context:

  • Neuromeningeal tuberculosis is a severe form of Mycobacterium tuberculosis infection affecting the brain and meninges.
  • This study examines cases in the northeastern suburbs of Paris, a region with a diverse population.

Purpose:

  • To analyze the epidemiological and clinical characteristics of neuromeningeal tuberculosis.
  • To identify factors influencing diagnosis and treatment outcomes.

Summary:

  • A retrospective study of 19 patients revealed that neuromeningeal tuberculosis primarily affects young, foreign-born individuals.
  • Clinical manifestations include weight loss, weakness, fever, and headache, with a significant diagnostic delay.
  • Cerebrospinal fluid cultures were more sensitive than direct examination for identifying Mycobacterium tuberculosis.

Impact:

  • Highlights the persistent challenge of delayed diagnosis in neuromeningeal tuberculosis, emphasizing its impact on prognosis.
  • Suggests the need for further research into optimal treatment durations and the role of corticosteroid therapy.

More Related Videos

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...