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Construction of heme enzymes: four approaches
1Center for Integrative Bioscience and Institute for Molecular Science, Okazaki National Research Institutes, 444-8585, Okazaki, Japan. yoshi@ims.ac.jp
Current Opinion in Chemical Biology
|June 1, 2002
Abstract:
Construction of enzymes that catalyze either desired reactions or exhibit desired substrate specificity is one of the goals of enzymatic study. Rational design of enzymes is an important approach in this field. Another, extremely different, methodology from rational design, directed evolution, has been rapidly developed over the past two years.