Related Experiment Videos
Effect of uterine horn ligation on bone mass: an experimental study in rats
Horatio Rico1, C Cuesta, J Cortés
1Department of Medicine and Medical Specialties, University of Alcalá de Henares, Madrid, Spain. horatio.rico@uab.es
Objective:
After tubal ligation, normal bone mass in the presence of gonadal deficit has been reported. These incongruent results motivated us to examine the topic.
Study Design:
Bone mass was assessed by densitometry and ultrasonography 60 days after surgery on 100-day-old female Wistar rats. Fifteen Wistar rats with uterine horn ligation (TL) were compared with 15 unoperated, 15 with a sham uterine horn ligation (Sham-TL), and 15 ovariectomized (OVX), using ANOVA and a correlation test to determine the relations between results.
Results:
Femoral and vertebral bone mass were significantly lower in the OVX y TL groups than in unoperated and controls groups (P<0.0001).
Conclusions:
Our study revealed significantly lower axial and peripheral bone mass in rats with uterine horn ligation.