Selective modulation of sex steroids

Jerald S Goldstein1, Cynthia K Sites

  • 1Department of Obstetrics and Gynecology, The University of Vermont College of Medicine, Given Building C-250, Burlington, VT 05405, USA.

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Dose-Response Relationship: Selectivity and Specificity

Drugs exert their therapeutic effects by interacting with receptors, enzymes, or ion channels that are present throughout the human body. The strength and duration of the interaction between a drug and its target receptor are characterized by the selectivity and specificity of the drug. Selectivity refers to a drug's strong preference for its intended target over other targets. For instance, isoprenaline, a non-selective β-adrenergic agonist, interacts with both β1- and β2-adrenergic receptors...
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Target Cell Response to Hormones

Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
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Regulation of Hormone Secretion

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Humoral stimuli,...
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Hormonal Regulation of the Menstrual Cycle

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