Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Organization of Genes02:07

Organization of Genes

Overview
Organization of Genes02:07

Organization of Genes

Overview
Synteny and Evolution02:31

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral chromosome underwent...
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Epistasis Analysis01:09

Epistasis Analysis

Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nature's strategies: Fish that switch sex to thrive.

Science (New York, N.Y.)·2018
Same author

Nature's strategies: Resilience by regeneration.

Science (New York, N.Y.)·2018
Same author

Tamed immune reaction aids pregnancy.

Science (New York, N.Y.)·2018
Same author

The runners up.

Science (New York, N.Y.)·2017
Same author

Breakdowns of the year.

Science (New York, N.Y.)·2017
Same author

Survey of archaea in the body reveals other microbial guests.

Science (New York, N.Y.)·2017

Related Experiment Video

Updated: Jul 6, 2026

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
14:06

Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

Published on: November 12, 2012

Genomics. Charting a genome's hills and valleys

Elizabeth Pennisi

    Science (New York, N.Y.)
    |June 1, 2002
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
    10:40

    Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

    Published on: December 22, 2017

    Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
    08:57

    Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

    Published on: August 14, 2018

    Related Experiment Videos

    Last Updated: Jul 6, 2026

    Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays
    14:06

    Mapping Bacterial Functional Networks and Pathways in Escherichia Coli using Synthetic Genetic Arrays

    Published on: November 12, 2012

    Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
    10:40

    Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

    Published on: December 22, 2017

    Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
    08:57

    Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

    Published on: August 14, 2018