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Measles in Thai adults: three case reports and management of contact cases
C Pancharoen1, S Wachirarojpaisan, S Pattamadilok
1Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. chitsanu.p@chula.ac.th
Abstract:
We report on three adults (one nurse and two medical students) diagnosed as having measles. All the patients presented with fever, cough, conjunctival injection and rash. They contracted measles from pediatric patients who had been treated at Chulalongkorn Hospital in the previous two weeks. Physical examination revealed Koplik's spots on the oral mucosa and typical maculopapular rash. The diagnosis was confirmed by viral isolation. Measles IgG antibodies were measured in 36 medical students who were in close contact with patient 2 and measles vaccines were given. Thirty-three specimens had positive measles IgG, two had equivocal results and one had negative result. The student with negative measles IgG eventually developed measles (patient 3). Except for patient 2 and 3, no further cases of measles were seen among the contacts.
Insights
Three healthcare professionals contracted measles from pediatric patients. Antibody testing in contacts revealed one unvaccinated student developed measles, highlighting the importance of vaccination.
Area of Science:
- Infectious Diseases
- Virology
- Epidemiology
Background:
- Measles is a highly contagious viral illness.
- Nosocomial transmission of measles can occur in healthcare settings.
- Healthcare workers and students are at risk of measles exposure.
Observation:
- Three adult healthcare workers (one nurse, two medical students) were diagnosed with measles.
- Patients presented with classic measles symptoms: fever, cough, conjunctival injection, and rash.
- Exposure occurred from pediatric patients treated at Chulalongkorn Hospital.
Findings:
- Physical examination confirmed Koplik's spots and maculopapular rash.
- Viral isolation confirmed the measles diagnosis.
- Measles IgG antibody testing in 36 close contacts showed 33 positive, 2 equivocal, and 1 negative result.
- The contact with negative IgG subsequently developed measles, indicating susceptibility.
Implications:
- This case series underscores the risk of measles transmission within hospitals.
- Prompt diagnosis and contact tracing are crucial for outbreak control.
- Ensuring healthcare personnel are adequately vaccinated against measles is vital for patient and staff safety.
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