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Measles in Thai adults: three case reports and management of contact cases

C Pancharoen1, S Wachirarojpaisan, S Pattamadilok

  • 1Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. chitsanu.p@chula.ac.th

Insights

Three healthcare professionals contracted measles from pediatric patients. Antibody testing in contacts revealed one unvaccinated student developed measles, highlighting the importance of vaccination.

Area of Science:

  • Infectious Diseases
  • Virology
  • Epidemiology

Background:

  • Measles is a highly contagious viral illness.
  • Nosocomial transmission of measles can occur in healthcare settings.
  • Healthcare workers and students are at risk of measles exposure.

Observation:

  • Three adult healthcare workers (one nurse, two medical students) were diagnosed with measles.
  • Patients presented with classic measles symptoms: fever, cough, conjunctival injection, and rash.
  • Exposure occurred from pediatric patients treated at Chulalongkorn Hospital.

Findings:

  • Physical examination confirmed Koplik's spots and maculopapular rash.
  • Viral isolation confirmed the measles diagnosis.
  • Measles IgG antibody testing in 36 close contacts showed 33 positive, 2 equivocal, and 1 negative result.
  • The contact with negative IgG subsequently developed measles, indicating susceptibility.

Implications:

  • This case series underscores the risk of measles transmission within hospitals.
  • Prompt diagnosis and contact tracing are crucial for outbreak control.
  • Ensuring healthcare personnel are adequately vaccinated against measles is vital for patient and staff safety.

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