Validation of the Cardiovascular Limitations and Symptoms Profile (CLASP) in chronic stable angina

Robert J P Lewin1, David R Thompson, Colin R Martin

  • 1Department of Health Sciences, University of York, York, UK.

Insights

The Cardiovascular Limitations and Symptoms Profile (CLASP) is a reliable and valid tool for assessing health-related quality of life in patients with chronic stable angina.

Area of Science:

  • Cardiology
  • Health Outcomes Research
  • Psychometrics

Background:

  • Chronic stable angina significantly impacts patients' quality of life.
  • Accurate assessment tools are crucial for evaluating interventions and patient well-being.

Purpose of the Study:

  • To establish the reliability, validity, and sensitivity of the Cardiovascular Limitations and Symptoms Profile (CLASP).
  • To evaluate CLASP's utility in patients with chronic stable angina.

Main Methods:

  • 226 patients with angina were randomized into three groups: angina management program, routine care, or exercise therapy.
  • Patients completed CLASP at baseline and 10 weeks, alongside SIP, HADS, and SPQ questionnaires.

Main Results:

  • CLASP demonstrated significant correlations with angina episodes, treadmill time, and quality of life measures (SIP, SPQ).
  • The CLASP subscales showed strong correlations with corresponding Sickness Impact Profile subscales, confirming validity.

Conclusions:

  • CLASP is a reliable, valid, and sensitive measure for assessing health-related quality of life in chronic stable angina patients.
  • Further validation in diverse cardiac patient groups (e.g., heart failure, post-MI) is recommended.
Abstract

Related Concept Videos

Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Angina V: Nursing Management01:20

Angina V: Nursing Management

Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...