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Related Experiment Videos

A 14-year-old girl with recumbent proteinuria.

M Khurram Faizan1, Laura S Finn, Angelisa M Paladin

  • 1Division of Nephrology, CH-46, Children's Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA 98105-0371, USA. kfaiza@chmc.org

Pediatric Nephrology (Berlin, Germany)
|June 4, 2002
PubMed
Summary

A splenic cyst caused a rare condition called nutcracker syndrome in a teen, leading to protein in her urine. Surgical removal of the cyst resolved the proteinuria, highlighting this unusual cause of kidney issues.

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Area of Science:

  • Nephrology
  • Radiology
  • Surgical Oncology

Background:

  • Proteinuria, or protein in the urine, can indicate kidney disease but may have other causes.
  • Nutcracker syndrome is a rare condition where the left renal vein is compressed, often between the superior mesenteric artery and the aorta.
  • Splenic cysts are fluid-filled sacs within the spleen, typically asymptomatic.

Observation:

  • A 14-year-old female presented with persistent nighttime proteinuria without other symptoms or signs of intrinsic renal disease.
  • Abdominal ultrasound revealed a large splenic cyst.
  • CT scan demonstrated that the splenic cyst was compressing the left renal vein.

Findings:

  • The splenic cyst caused extrinsic compression of the left renal vein, consistent with nutcracker syndrome.

Related Experiment Videos

  • Surgical removal of the splenic cyst led to the complete resolution of proteinuria.
  • This case highlights a rare etiology for nutcracker syndrome and subsequent proteinuria.

    • Implications:

    • Splenic cysts should be considered in the differential diagnosis of unexplained proteinuria, particularly in younger patients.
    • Compression of the left renal vein by adjacent masses can manifest as proteinuria.
    • Early diagnosis and intervention, such as cyst removal, can effectively manage proteinuria caused by nutcracker syndrome.