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Updated: Aug 9, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
[Surgical treatment of traumatic macular holes]
V Krásnik1, P Strmen, L Javorská
1Klinika oftalmológie LF UK, Bratislava.
Purpose:
To review the anatomic and visual outcomes of patients with traumatic macular hole, who underwent vitreoretinal surgery with membrane limitans interna (MLI) removal and using autologous serum.
Methods:
The retrospective review consists of 6 eyes of 6 patients with traumatic macular hole, who underwent pars plana vitrectomy with the removal MLI and with using autologous serum. This study includes 4 male and 2 female. Ages ranged from 10 to 34 years and all patients underwent surgery between February 1997 to October 2000. The time between the injury and surgery ranged from 3 days to 3 months. The aetiollogy was 5-times blunt trauma with ball during field games and once it was shot injury. The initial visual acuity and campimetry were recived and anatomical, functional results and campimetry every 3 months after surgery were reviewed.
Results:
Anatomical closure of the macular hole was achieved in 4 (66.6%) of the eyes (in 1 eye the closure was with pigmented scar). Two patients who have a persistent macular hole, underwent this surgery 2 or 3 months after injury. In all 4 eyes with anatomic closure of the macular hole was reduction of central scotoma. Postoperative Snellen visual acuity improved 3 or mole lines in the 2 eyes.
Conclusion:
Our results suggest that the period between injury and vitreoretinal surgery is very important for final anatomical and functional results after traumatic macular hole.

