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Updated: Aug 13, 2026

Analytical Techniques for Assaying Nitric Oxide Bioactivity
Published on: June 18, 2012
[Therapeutic use of nitric oxide: implications for nursing]
C M Santiago1, C H Fernandes, M S Nogueira
1Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo, Av. Bandeirantes, 3900-Monte Alegre-14040-902-Ribeirão Preto-São Paulo-Brasil.
Abstract:
Nitric oxide (NO) is a gas that transmits signals in the organism. Such signal transmission takes place by means of the gas synthesis and release in different cell types. After it is released, the gas penetrates the membrane of a neighboring cell and regulates its function. Such mechanism represents an entirely new signaling principle in biological systems. The discoverers of NO as a signaling molecule were awarded the Nobel Prize in Medicine and Physiology in 1998. This discovery has revolutionized medicine and originated new treatments for old problems. In this study, we review the role of NO in some pathologies such as sepsis, arterial hypertension and pulmonary hypertension and Nitric Oxide is explained in terms of its current merit for treatment and its impact on nursing care.
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