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Related Experiment Videos

Molybdenum in rat tissue.

R Pande1, R Kumar, S P Singh

  • 1Department of Zoology, University of Lucknow, Uttar Pradesh, India. ratnap23@sify.com

Human & Experimental Toxicology
|June 6, 2002
PubMed
Summary
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Male rats exposed to molybdenum (Mo) showed increased tissue concentrations of the metal. Kidney tissues accumulated the highest levels of Mo, indicating significant uptake and retention in the body.

Area of Science:

  • Toxicology
  • Environmental Health
  • Biochemistry

Background:

  • Molybdenum (Mo) is an essential trace element, but excessive intake can lead to toxicity.
  • Understanding Mo distribution and accumulation in tissues is crucial for assessing potential health risks.

Purpose of the Study:

  • To investigate the tissue distribution and accumulation of molybdenum in male rats following oral administration.

Main Methods:

  • Male rats were administered sodium molybdate (50 mg/kg) in drinking water for eight consecutive doses.
  • Molybdenum concentrations were measured in various body tissues and blood cells.

Main Results:

  • Oral administration of molybdenum led to a significant increase in Mo concentration across body tissues.

Related Experiment Videos

  • The highest accumulation of molybdenum was observed in kidney tissues.
  • Blood cells exhibited the lowest concentrations of molybdenum.

    • Conclusions:

    • The study demonstrates significant accumulation of molybdenum in rat tissues, particularly the kidney.
    • These findings highlight the potential for molybdenum to accumulate in organs following repeated exposure.