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Published on: September 25, 2017
Interventions for aortic coarctation
T S Hornung1, L N Benson, P R McLaughlin
1Division of Cardiology, Green Lane Hospital, Auckland, New Zealand.
Insights
Catheter interventions, including balloon angioplasty and stenting, are effective treatments for coarctation of the aorta. These minimally invasive options offer good success rates and safety profiles for adult patients.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Background:
- Coarctation of the aorta traditionally treated with surgery.
- Catheter interventions have emerged as a viable alternative over the past two decades.
Purpose of the Study:
- To evaluate the efficacy and safety of catheter interventions for coarctation of the aorta.
- To compare balloon angioplasty and primary stent implantation.
- To determine optimal initial therapy for adult patients.
Main Methods:
- Review of balloon angioplasty and primary stent implantation for coarctation of the aorta.
- Analysis of outcomes including gradient reduction, restenosis, and aneurysm formation.
- Comparison of results for native and recurrent coarctation.
Main Results:
- Balloon angioplasty achieves satisfactory gradient reduction in ~80% of patients; restenosis and aneurysm rates <10%.
- Primary stent implantation shows low rates of suboptimal gradient reduction (<5%), restenosis (<5%), and complications (<5%).
- Outcomes for native and recurrent coarctation are similar with catheter interventions.
Conclusions:
- Catheter interventions are established, safe, and effective for coarctation of the aorta.
- Both balloon angioplasty and stenting demonstrate good success rates.
- Catheter intervention should be considered the initial therapy for most adult patients.
Abstract:
The standard treatment of coarctation of the aorta is surgical. In the last 2 decades, however, treatment by catheter intervention has become more widespread, using either balloon angioplasty or primary stent implantation. Balloon angioplasty was originally used for recurrent coarctation after surgical repair but has now been shown equally effective for unoperated coarctation. The procedure produces a satisfactory gradient reduction in approximately 80% of patients, with transverse arch hypoplasia the main predictor of poorer outcome. Rates of restenosis and aneurysm formation are less than 10%. Primary stent implantation has been suggested as an option potentially superior to angioplasty alone. Stent implantation limits elastic recoil and potentially reduces aneurysm formation by reducing the amount of balloon stretch required. The incidence of suboptimal gradient reduction is low, probably 5% or less, as is the rate of restenosis. Aneurysm formation, vascular complications, and stent migration also occur in less than 5%. Catheter interventions are now an established treatment strategy for coarctation, with a good success rate and safety profile. The outcome for native and recurrent coarctation appears similar. The authors believe that for most adult patients with coarctation of the aorta, catheter intervention should be offered as initial therapy.
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