Corticosteroid-like effect of cyproterone and cyproterone acetate in mice

Cyproterone and cyproterone acetate exert the corticoid-like effect on the adrenal and spleen weight in the mice. When compared with prednisone, cyproterone acetate has approximately 1/5 of the corticoid potency of prednisone, expressed by the decrease of the spleen weight.