Related Experiment Video
Updated: Feb 22, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
12.4K
Correlation between oral malodor and periodontal bacteria
Yoshio Nakano1, Mamiko Yoshimura, Toshihiko Koga
1Department of Preventive Dentistry, Kyushu University Faculty of Dental Science, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. yosh@dent.kyushu-u.ac.jp
Microbes and Infection
|June 6, 2002
Summary
Volatile sulfur compounds (VSCs) cause bad breath. Researchers identified a key gene in Porphyromonas gingivalis responsible for producing methyl mercaptan, a major VSC contributing to oral malodor.
Area of Science:
- Microbiology
- Biochemistry
- Oral Health
Background:
- Volatile sulfur compounds (VSCs) are the primary cause of oral malodor.
- Key VSCs include hydrogen sulfide, methyl mercaptan, and dimethyl sulfide.
Purpose of the Study:
- To discuss the mechanism of VSC formation by oral bacteria.
- To elucidate the pathogenic role of VSCs in oral malodor.
Main Methods:
- Cloning of the mgl gene from Porphyromonas gingivalis.
- Analysis of the enzyme L-methionine-alpha-deamino-gamma-mercaptomethane-lyase function.
Main Results:
- The mgl gene encodes an enzyme crucial for methyl mercaptan production.
- Porphyromonas gingivalis is identified as a source of methyl mercaptan.
Conclusions:
- Understanding VSC formation mechanisms is vital for addressing oral malodor.
- The mgl gene and its product play a significant role in the pathogenesis of bad breath.
Related Concept Videos
01:26Assessment of the Mouth
1.3K
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
1.3K
01:15Teeth
1.9K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.9K
01:11Oral Cavity
3.3K
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
3.3K