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Related Experiment Videos

Sinistrality in schizophrenia.

Jacqueline J A Buijsrogge1, Karim Benali, Perrine Brazo

  • 1Groupe d'Imagerie Neurofonctionnelle(GIN), Unité Mixte de Recherche 6095, CNRS/CEA, Université de Caen, Université de Paris V and Centre Esquirol, Centre Hospitalier et Universitaire Caen, 14000, France.

Schizophrenia Research
|June 6, 2002
PubMed
Summary
This summary is machine-generated.

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Schizophrenic patients do not exhibit a significant shift towards non-right handedness (sinistrality) compared to controls. This finding holds true even when considering sex and using a detailed handedness evaluation.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Human Behavior

Background:

  • Sinistrality, or increased non-right handedness, has been anecdotally linked to schizophrenia.
  • Previous studies show conflicting results due to variations in assessing handedness and accounting for sex.

Purpose of the Study:

  • To investigate if schizophrenic patients exhibit a sinistral shift in handedness compared to controls.
  • To account for the influence of sex and utilize a continuum scoring system for handedness evaluation.

Main Methods:

  • Seventy-three patients diagnosed with schizophrenia (DSM-IV) and 81 healthy controls were assessed.
  • The Edinburgh Handedness Inventory (EHI) was employed for a comprehensive evaluation of handedness.

Main Results:

Related Experiment Videos

  • No statistically significant difference in mean EHI scores was found between schizophrenic patients and the control group, after controlling for sex.
  • The analysis did not reveal a sinistral shift in handedness for the schizophrenic cohort.

Conclusions:

  • Schizophrenia, as a whole, does not demonstrate an increased prevalence of sinistrality when handedness is assessed using a continuum score and sex is considered.
  • The study suggests that previous discrepancies in sinistrality findings in schizophrenia may be attributed to methodological differences.