The diversity of acetylated proteins

Acetylation of proteins, either on various amino-terminal residues or on the epsilon-amino group of lysine residues, is catalyzed by a wide range of acetyltransferases. Amino-terminal acetylation occurs on the bulk of eukaryotic proteins and on regulatory peptides, whereas lysine acetylation occurs at different positions on a variety of proteins, including histones, transcription factors, nuclear import factors, and alpha-tubulin.