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Immunotherapy of multiple sclerosis--current practice and future directions.
Mark J Tullman1, Fred D Lublin, Aaron E Miller
1The Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Mount Sinai Medical Center, New York, NY 10029, USA. gmtullman@aol.com
Journal of Rehabilitation Research and Development
|June 8, 2002
Summary
Multiple sclerosis (MS) treatments have advanced, offering options for various disease forms. Current therapies modestly slow progression, but significant improvements are needed for a potential cure.
Area of Science:
- Neurology
- Immunology
- Pharmacology
Background:
- Multiple sclerosis (MS) is now a treatable neurological condition.
- Significant advancements in understanding MS pathogenesis have occurred over the last decade.
Purpose of the Study:
- To review existing and emerging therapies for multiple sclerosis.
- To discuss the current treatment landscape and future directions for MS management.
Main Methods:
- Literature review of immunosuppressive and immunomodulatory therapies for MS.
- Analysis of treatment efficacy across different MS subtypes (relapsing-remitting, secondary progressive, progressive relapsing).
Main Results:
- Immunosuppressive and immunomodulatory drugs can modify the long-term course of MS.
- Available therapies demonstrate modest effects in reducing relapse rates and slowing disease progression.
Conclusions:
- Current MS therapies offer benefits but have limitations in their impact.
- Further research is crucial to enhance treatment efficacy and pursue a cure for multiple sclerosis.