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Updated: Sep 1, 2026

Development and Identification of a Novel Subpopulation of Human Neutrophil-derived Giant Phagocytes In Vitro
Published on: January 25, 2017
Neutrophil hypersegmentation in children with iron deficiency anemia
Tansu Sipahi1, Betül Tavil, Yücel Unver
1Dr. Sami Ulus Children's Hospital, Ankara, Turkey. tansusipahi@hotmail.com
Abstract:
Neutrophil hypersegmentation (NH) is usually associated with vitamin B12 or folic acid deficiency. NH is seen in iron deficiency anemia but there are very few case studies about this. Neutrophil hypersegmentation was evaluated in 94 children with iron deficiency anemia; 23 healthy children comprised the control group with similar ages. NH was found in 76/94 (81%) in the study group and 2/23 (9%) of the control group. The difference was statistically significant (p < .01).

