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Related Experiment Videos

Interest in BRCA1/2 testing in a primary care population.

Katrina Armstrong1, Barbara Weber, Peter A Ubel

  • 1Department of Medicine, University of Pennsylvania School of Medicine, USA. karmstro@mail.upenn.edu

Preventive Medicine
|June 8, 2002
PubMed
Summary

Awareness of BRCA1/2 testing is lower among African-American women. Women at lowest risk for BRCA mutations show the most interest in testing when given limited information.

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Area of Science:

  • Genetics
  • Oncology
  • Public Health

Background:

  • BRCA1/2 gene mutations are rare in the general population.
  • Targeted testing for BRCA1/2 mutations is recommended for women with risk factors.
  • BRCA1/2 testing costs are decreasing, potentially leading to wider use in primary care with limited pre-test counseling.

Purpose of the Study:

  • Investigate factors associated with interest in BRCA1/2 testing among primary care patients.
  • Assess patient interest with limited pre-test information.

Main Methods:

  • Cross-sectional mailed survey.
  • 400 adult women from a University-based General Internal Medicine practice.
  • Data collected on awareness and interest in BRCA1/2 testing.

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Main Results:

  • 53% of respondents were aware of BRCA1/2 testing; 58% were interested.
  • Awareness was lower in African-American women and higher with college education.
  • Interest in testing was lower with family history of breast cancer and increasing age.

Conclusions:

  • African-American women have lower awareness of BRCA1/2 testing in primary care settings.
  • Women at lowest risk showed the most interest in testing when provided limited information.
  • Challenges include managing "worried well" and ensuring access for high-risk women of all races.