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Updated: Aug 19, 2026
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Intravital Microscopy of the Mouse Brain Microcirculation using a Closed Cranial Window
Published on: November 19, 2010
Ventral burn in rats: an experimental model for intravital microscopic study of microcirculation
1Department of Surgery, Scott and White Clinic, Scott, Sherwood and Brindley Foundation, 702 SW HK Dodgen Loop #206C, Temple, TX 76504, USA. korompai@msn.com
Abstract:
A novel technique of application of controlled ventral scald burn to rodent, whose back is inaccessible because of preburn preparation, is described. Boiling water is applied across a polyethylene membrane that partially envelops the subject. The technique is simple, economical, reproducible and allows intravital microscopic study of microcirculation in a remote muscular bed before and after burn injury.
