Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bacterial anti-apoptotic activities.

Georg Häcker1, Silke F Fischer

  • 1Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Trogerstr. 9, D-81675, Munich, Germany. hacker@lrz.tum.de

FEMS Microbiology Letters
|June 8, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<i>Coxiella burnetii</i> Infection Among Blood Donors From Baden-Wuerttemberg Province and Hesse Province, Germany: A Multicentre Cross-Sectional Serological Study.

Public health challenges·2026
Same author

MTCH2 promotes BAX and BAK self-assembly and apoptotic pore growth.

Nature structural & molecular biology·2026
Same author

[Coxiella burnetii in small ruminants - managing the zoonotic pathogen].

Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere·2026
Same author

All-cause mortality and risk factors for death in patients with Clostridioides difficile infections: a prospective multi-centre cohort study in six German university hospitals, 2016-2020.

The Journal of hospital infection·2026
Same author

Altered Pathogen Spectrum of Spontaneous Bacterial Peritonitis in Patients Treated With Proton Pump Inhibitors.

Alimentary pharmacology & therapeutics·2026
Same author

The second mitochondrial activator of caspases (SMAC) regulates growth, inflammation and mitochondrial integrity in cancer cells.

Cell death and differentiation·2026

Bacteria can inhibit apoptosis, a common cell death process. This review explores how bacterial interactions with host cells lead to apoptosis resistance, impacting infection outcomes.

Area of Science:

  • Microbiology
  • Cell Biology
  • Immunology

Background:

  • Apoptosis, or programmed cell death, is a fundamental biological process.
  • Apoptosis plays a role in multicellular organisms and during microbial infections.
  • Some bacteria can interfere with or prevent host cell apoptosis.

Purpose of the Study:

  • To review the anti-apoptotic activities of various bacteria.
  • To elucidate the mechanisms by which bacteria inhibit apoptosis.
  • To understand the interplay between bacterial-host cell contact and apoptosis resistance.

Main Methods:

  • Literature review of studies on bacterial modulation of apoptosis.
  • Analysis of molecular pathways involved in apoptosis induction and inhibition.

Related Experiment Videos

  • Examination of host and bacterial contributions to apoptosis resistance.

    • Main Results:

    • Certain bacteria possess mechanisms to resist or inhibit host cell apoptosis.
    • Bacterial interactions can decrease mammalian cell susceptibility to apoptosis.
    • The specific contributions of bacterial and host factors to this interaction are being elucidated.

    Conclusions:

    • Bacterial inhibition of apoptosis is a significant factor in infectious diseases.
    • Understanding these mechanisms can reveal new therapeutic targets.
    • Further research is needed to fully comprehend the molecular basis of bacterial anti-apoptotic strategies.