Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cognitive patterns in subtypes of schizophrenia.

P Brazo1, R M Marié, I Halbecq

  • 1Centre Esquirol, Centre Hospitalier Universitaire (CHU), Avenue Côte de Nacre, 14033, Caen, France. dollfus-s@chu-caen.fr

European Psychiatry : the Journal of the Association of European Psychiatrists
|June 8, 2002
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient room-temperature synthesis of crosslinked polyhydroxyurethanes from 5-membered cyclic carbonates without solvent or catalyst.

Faraday discussions·2025
Same author

Experimental validation in a neutron exposure frame of the MINAS TIRITH for cell damage simulation.

Physics in medicine and biology·2023
Same author

[Design, implementation and evaluation of an educational approach for patients with PICC line and midline].

Annales pharmaceutiques francaises·2023
Same author

MINAS TIRITH: a new tool for simulating radiation-induced DNA damage at the cell population level.

Physics in medicine and biology·2023
Same author

Chemical sex (chemsex) in a population of French university students.

Dialogues in clinical neuroscience·2022
Same author

Antipsychotic drug dose in real-life settings results from a Nationwide Cohort Study.

European archives of psychiatry and clinical neuroscience·2021

Schizophrenia subtypes show distinct cognitive deficits. The positive subtype retains some cognitive skills, while deficit and disorganized subtypes exhibit significant executive and memory impairments.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Schizophrenia is a complex disorder with significant heterogeneity.
  • Understanding cognitive patterns in different schizophrenia subtypes is crucial for targeted interventions.

Purpose of the Study:

  • To investigate distinct cognitive profiles across different schizophrenia subtypes.
  • To identify specific patterns of executive/attentional and memory dysfunction in schizophrenia patients.

Main Methods:

  • Thirty-five schizophrenia patients (categorized into deficit, disorganized, and positive subtypes) and 35 healthy controls were assessed.
  • Cognitive functions, including executive/attentional abilities and episodic memory, were evaluated using standardized tests (MCST, verbal fluency, TMT, Stroop, CVLT).

Related Experiment Videos

Main Results:

  • The positive schizophrenia subtype demonstrated largely preserved executive/attentional and memory functions compared to controls.
  • Deficit and disorganized subtypes exhibited significant executive/attentional and memory impairments.
  • The deficit subtype showed deficits in card sorting and fluency, while the disorganized subtype performed poorly on trail making and Stroop tests.

Conclusions:

  • Distinct cognitive patterns exist among schizophrenia subtypes, highlighting the disorder's cognitive heterogeneity.
  • These findings suggest that cognitive dysfunction in schizophrenia is not uniform and varies significantly across patient subgroups.