Related Experiment Videos

Prediction of outcomes in hypertensive patients with suspected coronary disease

Thomas H Marwick1, Colin Case, Stephen Sawada

  • 1University of Queensland, Brisbane, Australia. tmarwick@medicine.pa.uq.edu.au

Hypertension (Dallas, Tex. : 1979)
|June 8, 2002
PubMed

Insights

Stress echocardiography effectively predicts cardiac death in hypertensive patients. Abnormalities like ischemia on stress echocardiograms indicate higher mortality risk, offering valuable prognostic information.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Clinical Prognostics

Background:

  • Stress echocardiography aids coronary artery disease diagnosis in hypertension.
  • Its prognostic value for mortality prediction in this population remains unclear.

Purpose of the Study:

  • To assess stress echocardiography's ability to predict mortality in hypertensive patients.
  • To determine if stress echocardiography results offer incremental prognostic value.

Main Methods:

  • Prospective follow-up of 2363 hypertensive patients for up to 10 years.
  • Analysis of stress echocardiogram findings (normal, resting LV dysfunction, ischemia).
  • Evaluation of exercise vs. dobutamine stress echocardiography outcomes.

Main Results:

  • Stress echocardiography identified ischemia as an independent predictor of mortality.
  • Negative stress echocardiograms showed a low annual death risk (<1%).
  • Echocardiography results added prognostic power to clinical and exercise data.

Conclusions:

  • Stress echocardiography is an independent predictor of cardiac death in hypertensive patients.
  • It provides prognostic information incremental to clinical risk factors and exercise tests.
  • Abnormalities like ischemia on stress echocardiograms are significant indicators of mortality risk.

Keywords:
Non-programmatic

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...