Related Experiment Video
Updated: Sep 30, 2026

Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published on: July 16, 2018
[Proposing surgical management to a patient with low-grade glioma: controversies and ethical consequences]
1Service de Neurochirurgie, Hôpital de la Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris Cedex 13, France. manuel.lopes@psl.ap-hop-paris.fr
Abstract:
The therapeutic controversies surrounding low-grade glioma result mainly from the lack of certainty about their histological definition, and, from our imperfect knowledge of the natural history of the disease. Heterogeneous surgical management is the consequence of this situation, which renders difficult to propose the best attitude to each individual patient, thus raising ethical questions, because the absence of a consensus. Performing prospective studies able to analyse these different modalities is mandatory whenever we want to be enable to give to our patients the best answer in their precise case, and furthermore to justify back our acts too.