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[Evaluation of systematic pulmonary function testing for asthma in children aged three to five years]

D Siret1, C Paruit, V David

  • 1Clinique médicale pédiatrique, hôpital de la Mère et de l'Enfant, CHU Nantes, 9 Quai-Moncousu, 44093 Nantes, France. pediatrie@chsn.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|June 11, 2002
PubMed

Insights

Pulmonary function testing using flow-volume loops and interrupter resistance is feasible and reproducible in preschool children with asthma. Interrupter resistance better correlates with clinical asthma symptoms.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Asthma Research

Context:

  • Pulmonary function testing (PFT) is underutilized in preschool children with asthma.
  • Early airway function deterioration in pediatric asthma is increasingly recognized.
  • Assessing PFT feasibility and clinical utility in young children is crucial.

Purpose:

  • To evaluate the feasibility and clinical interest of flow-volume loops and interrupter resistance measurements in preschool children with asthma.
  • To assess the reproducibility of these pulmonary function tests (PFTs) in a young pediatric population.
  • To determine the correlation between PFT results and clinical parameters in preschool asthmatics.

Summary:

  • Flow-volume loops and interrupter resistance measurements were performed before and after salbutamol inhalation in 75 children aged 3-5 years with asthma.
  • Feasibility (92%) and reproducibility (91%) rates were high, with 84% of tests being exploitable.
  • Interrupter resistance showed significant associations with nocturnal symptoms, exercise-induced symptoms, daytime symptoms, and lack of inhaled corticosteroid treatment, outperforming flow-volume loops in clinical correlation.

Impact:

  • Demonstrates that PFTs, specifically interrupter resistance, are viable and reproducible in preschool children with asthma.
  • Highlights the potential of interrupter resistance to guide clinical management and treatment modifications in this age group.
  • Supports the integration of PFTs into routine asthma care for preschool-aged children, leading to improved diagnostic accuracy and treatment adjustments.
Abstract

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