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Updated: Aug 8, 2026

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
Published on: March 25, 2014
Epitope identification and vaccine design for cancer immunotherapy
Alessandro Sette1, Elissa Keogh, Glenn Ishioka
1Epimmune Inc, San Diego, CA 92121, USA. asette@epimmune.com
Abstract:
The development of processes for engineering multi-epitope vaccines based on the identification and selection of epitope packages, along with vaccine design optimization using epitope placements and spacers to optimize processing efficacy, are reviewed. The Epimmune Inc epitope identification process has been applied to numerous cancer types, but also applies to infectious diseases. Epitope-analog efforts in novel vaccine design have also been explored and their uses in prophylactic and therapeutic applications are eagerly anticipated.
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