Related Experiment Video

Updated: Aug 9, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
07:55

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection

Published on: November 3, 2012

Relationship of contact lenses, pregnancy, and herpes simplex virus

Satya V Reddy, Bruce H Koffler

    The CLAO Journal : Official Publication of the Contact Lens Association of Ophthalmologists, Inc
    |June 11, 2002
    PubMed

    Herpes simplex virus (HSV) is one of the most common causes of corneal infections in the world, affecting more than 500,000 people in the United States alone. HSV keratitis recurrences can occur with systemic immunosuppression. Pregnancy can resemble a modified state of immunosuppression resulting in an increased risk for HSV keratitis. This type of immunosuppression combined with contact lens wear may have an additive effect and increase the possibility of HSV recurrence. Despite the obvious correlation, there are no reported cases in the literature. A case of bilateral HSV keratitis in a pregnant contact lens wearer is presented with an explanation of the causes and possible treatment methods.

    More Related Videos

    A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation12:22

    A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

    Published on: April 2, 2012

    Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals08:31

    Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals

    Published on: September 20, 2021

    Related Concept Videos

    Sexually Transmitted Infections01:26

    Sexually Transmitted Infections

    Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
    Acne Infection01:27

    Acne Infection

    Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
    Herpes01:28

    Herpes

    Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
    Chickenpox01:20

    Chickenpox

    Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
    Cytomegalovirus Disease01:27

    Cytomegalovirus Disease

    Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
    Genital Herpes01:23

    Genital Herpes

    Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...