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Clinic and ambulatory heart rate in sustained and white-coat hypertension

S D Pierdomenico1, A Bucci, D Lapenna

  • 1Centro per lo Studio dell'Ipertensione Arteriosa, delle Dislipidemie e dell'Arteriosclerosi, Dipartimento di Medicina e Scienze dell'Invecchiamento, University Gabriele d'Annunzio, Chieti, Italy. pierdomenico@unich.it

Blood Pressure Monitoring
|June 11, 2002
PubMed

Insights

White-coat hypertension patients have similar clinic heart rates but lower ambulatory heart rates than sustained hypertensives. This suggests white-coat hypertensives may face reduced cardiovascular risk.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Clinical Physiology

Background:

  • Distinguishes sustained and white-coat hypertension based on out-of-clinic blood pressure.
  • Highlights limited data on heart rate variations in these hypertensive groups.
  • Addresses the need to compare clinic and ambulatory heart rates.

Purpose of the Study:

  • To evaluate clinic and ambulatory heart rates in sustained hypertensives, white-coat hypertensives, and normotensives.
  • To compare heart rate patterns between different hypertensive states and control groups.
  • To investigate potential differences in cardiovascular risk indicators.

Main Methods:

  • Recruited 236 sustained hypertensives, 236 white-coat hypertensives, and 236 normotensives, matched for age, gender, BMI, and occupation.
  • Conducted clinic evaluations and non-invasive monitoring of blood pressure and heart rate.
  • Defined white-coat hypertension as clinic hypertension with daytime blood pressure < 135/85 mmHg.

Main Results:

  • Clinic heart rate was significantly higher in sustained and white-coat hypertensives compared to normotensives.
  • Daytime, night-time, and 24-hour ambulatory heart rates were significantly higher in sustained hypertensives versus white-coat hypertensives and normotensives.
  • Observed trends remained consistent when analyzing men and women separately.

Conclusions:

  • Clinic heart rate is comparable between sustained and white-coat hypertensives.
  • Ambulatory heart rate is lower in white-coat hypertensives, reflecting a reduced 24-hour heart rate load.
  • Findings suggest white-coat hypertensives may have a lower cardiovascular risk profile than sustained hypertensives.
Abstract

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