Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ion trap mass spectrometry: a personal perspective.

George Stafford1

  • 1LC and LC/MS Division, Thermo Finnigan, San Jose, California 95134, USA. gstafford@thermofinnigan.com

Journal of the American Society for Mass Spectrometry
|June 12, 2002
PubMed
Summary

This paper reviews the commercialization of the three-dimensional quadrupole ion trap mass spectrometer, tracing its development from 1953 through key technical breakthroughs to its present-day commercial success.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improved Protein and PTM Characterization with a Practical Electron-Based Fragmentation on Q-TOF Instruments.

Journal of the American Society for Mass Spectrometry·2021
Same author

High-Resolution Ion-Mobility-Enabled Peptide Mapping for High-Throughput Critical Quality Attribute Monitoring.

Journal of the American Society for Mass Spectrometry·2021
Same author

Rapid screening methods for yeast sub-metabolome analysis with a high-resolution ion mobility quadrupole time-of-flight mass spectrometer.

Rapid communications in mass spectrometry : RCM·2019
Same author

SPE-IMS-MS: An automated platform for sub-sixty second surveillance of endogenous metabolites and xenobiotics in biofluids.

Clinical mass spectrometry (Del Mar, Calif.)·2017
Same author

Evaluation of drift gas selection in complex sample analyses using a high performance drift tube ion mobility-QTOF mass spectrometer.

The Analyst·2015
Same author

Basic vapor exposure for tuning the charge state distribution of proteins in negative electrospray ionization: elucidation of mechanisms by fluorescence spectroscopy.

Journal of the American Society for Mass Spectrometry·2012

Area of Science:

  • Analytical Chemistry
  • Mass Spectrometry Technology

Background:

  • The three-dimensional quadrupole ion trap mass spectrometer has a history dating back to 1953.
  • Its development can be segmented into distinct historical phases.

Purpose of the Study:

  • To provide a personal perspective on the commercial development of the ion trap mass spectrometer.
  • To document key technical advancements and commercialization milestones.

Main Methods:

  • Historical review of ion trap technology.
  • Analysis of commercialization stages and breakthroughs.

Main Results:

  • The paper details the evolution of ion trap technology across three developmental ages.
  • It highlights critical technical innovations that enabled commercial viability.

Conclusions:

  • The commercial success of the three-dimensional quadrupole ion trap mass spectrometer is a result of sustained innovation.
  • The paper offers insights into the trajectory of this analytical instrument.

Related Experiment Videos