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Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
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Enzyme-based therapy for autism spectrum disorders -- is it worth another look?
Mark A Brudnak1, Bernard Rimland, Roy E Kerry
1Autism Research Institute, San Diego, CA, USA.
Medical Hypotheses
|June 12, 2002
Summary
This study explored the exorphin theory of autism, suggesting dietary enzyme therapy may help. Supplementing with ENZYMAID showed significant improvements in autism spectrum disorder (ASD) patients.
Area of Science:
- Neuroscience
- Biochemistry
- Developmental Pediatrics
Background:
- Autism Spectrum Disorder (ASD) is a developmental condition with limited treatment options.
- Nutritional interventions are being explored, including enzyme therapy for exorphins.
- The exorphin theory proposes neuroactive peptides contribute to ASD etiology.
Purpose of the Study:
- To investigate the exorphin theory of autism.
- To evaluate the efficacy of a novel dietary enzyme formulation, ENZYMAID, in treating ASD.
- To present new data supporting the role of enzymes in autism.
Main Methods:
- A study involving 46 patients aged 5-31 diagnosed with ASD.
- 12-week supplementation with the dietary enzyme formulation ENZYMAID.
- Symptom tracking using the Symptom Outcome Survey (SOS) method.
Main Results:
- ENZYMAID demonstrated safe and beneficial effects across all 13 measured parameters.
- Observed improvements in ASD symptoms ranged from 50% to 90%.
- Data suggests a critical role for enzymes in managing ASD.
Conclusions:
- Dietary enzyme therapy, specifically with ENZYMAID, shows promise as a viable treatment option for ASD.
- The findings support the exorphin theory and the therapeutic potential of enzyme supplementation.
- Further controlled studies are warranted to confirm these results.
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