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Phage lambda red-mediated adaptive mutation
Anthony R Poteete1, Hsinju R Wang, Patricia L Foster
1Department of Molecular Genetics & Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. anthony.poteete@umassmed.edu
Journal of Bacteriology
|June 12, 2002
Abstract:
Replacement of the recBCD genes of Escherichia coli with the red recombination genes of bacteriophage lambda results in a strain in which adaptive mutation occurs at an elevated frequency. Like RecBCD-dependent adaptive mutation, Red-mediated adaptive mutation is dependent upon recA and ruvABC functions.