Related Experiment Video
Updated: Aug 15, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[Cushing's disease in children and adolescents]
1Service d'Endocrinologie Pédiatrique, Hôpital Saint-Vincent-de-Paul, Paris, France.
Abstract:
Fifty-seven unselected children and adolescents with Cushing's disease underwent transsphenoidal exploration and microadenomectomy before their 16th birthday. Hypercortisolism was corrected in 42 of the 57 patients (74%). The recurrence rate was 17% and the long-term remission rate was 57%. Diagnostic peculiarities specific surgical problems and outcome were reviewed. Direct transnasal submucosal surgery for Cushing's disease is successful, and pituitary function can be preserved in most of these young patients.
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