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Published on: September 15, 2023
[Influence of preoperative factors on off-pump coronary aortic bypass grafting success]
H Nakano1, K Hayashi, M Daimon
1Department of Cardiovascular Surgery, Tokyo Medical University, Kasumigaura Hospital, Ibaraki, Japan.
Insights
Off-pump coronary artery bypass grafting (OPCAB) is feasible when preoperative pulmonary capillary wedge pressure and left ventricular end-diastolic pressure are within normal limits. These factors, not left ventricular volume, predict successful OPCAB outcomes.
Area of Science:
- Cardiovascular Surgery
- Cardiac Anesthesia
- Thoracic Surgery
Context:
- Off-pump coronary artery bypass grafting (OPCAB) aims to reduce myocardial injury and improve outcomes by avoiding cardiopulmonary bypass.
- Hemodynamic instability during OPCAB can arise from heart displacement, necessitating identification of predictive preoperative factors.
- This study investigates preoperative hemodynamic parameters influencing the success of OPCAB.
Purpose:
- To identify preoperative factors associated with hemodynamic stability during off-pump coronary artery bypass grafting (OPCAB).
- To compare patient characteristics and outcomes between OPCAB and conventional on-pump coronary artery bypass grafting (NOPCAB).
Summary:
- Forty-two patients underwent OPCAB and nine underwent NOPCAB. No OPCAB cases required conversion to on-pump procedures.
- The OPCAB group exhibited significantly lower preoperative pulmonary capillary wedge pressure (PCW) and left ventricular end-diastolic pressure (LVEDP) compared to the NOPCAB group.
- Normal PCW and LVEDP were identified as key factors for successful OPCAB, while increased left ventricular volume did not impact success rates.
Impact:
- Findings suggest that preoperative PCW and LVEDP within normal ranges are crucial for successful OPCAB.
- This research aids in patient selection for OPCAB, potentially improving surgical planning and patient outcomes.
- The study highlights the importance of hemodynamic assessment in optimizing patient suitability for minimally invasive cardiac surgery techniques.
Abstract:
Heart displacement during off-pump CABG (OPCAB) might induce the hemodynamic instability. We attempted to show which preoperative factors would contribute to an increase in that incident during OPCAB. Between February 2000, and October 2000, 51 patients underwent CABG in Okamura Memorial Hospital. Of these patients, 42 patients (82.4%) underwent OPCAB and 9 patients (17.6%) were operated upon under cardiac arrest with cardiopulmonary bypass (NOPCAB). To expose target coronary arteries for OPCAB, 3 deep pericardial traction stitches were placed near the left lower pulmonary vein (LPV), the left of the inferior vena cava (IVC) and the mid portion between LPV and IVC. To further assist in providing good presentation, patients were placed in Trendelenburg position (30 degree head-down tilt) and the right decubitus (30 degree the right side-down tilt). There were no OPCAB patients to be converted to on-pump CABG during anastomosis. Mean number of grafts in OPCAB group was 2.5 +/- 0.1 per patient, while that in NOPCAB group was 3.4 +/- 0.2 (p < 0.01). The bypass patient rate were 97.1% (100/103) in OPCAB group and 100% (31/31) in NOPCAB group (p = NS). In both groups, bilateral internal thoracic arteries were actively used for reperfusion to the left coronary artery. In the preoperative catheterization findings, pulmonary capillary wedge pressure (PCW) and left ventricular end-diastolic pressure (LVEDP) were significantly higher in NOPCAB group than those in OPCAB group (PCW: 14.0 vs 7.9 mmHg, LVEDP: 14.0 vs 8.7 mmHg: p < 0.05), and there was a tendency of low preoperative ejection fraction (EF) and cardiac index (CI) in NOPCAB group compared with those in OPCAB group, although there were no differences in left ventricular end-diastolic and end-systolic volume index (LVEDVI and LVESVI) between both groups. These findings suggested that PCW and LVEDP within the normal limit could be credited for the success with OPCAB, while an increase of the left ventricular volume would not contribute to the actual success.
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