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Platelet antiaggregatory effects and haemodynamic activity of two terfuroxan isomer pairs
Clara Cena1, Sonja Visentin, Annalisa Gasco
1Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Turin, Italy.
Abstract:
A couple of terfuroxan isomer pairs 1a,b and 2a,b were studied for their in vivo vasodilating activity and in vitro antiplatelet action. The haemodynamic profiles of the products resemble that of other NO-donors. Their in vitro antiaggregating activity is influenced both by terfuroxan system and by the substituents.