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Updated: Sep 30, 2026

Induction of Adhesion-dependent Signals Using Low-intensity Ultrasound
Published on: May 8, 2012
The effects of low-intensity pulsed ultrasound on bioabsorbable self-reinforced poly L-lactide screws
Lauri Handolin1, Timo Pohjonen, Esa K Partio
1Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Finland. lauri.handolin@hus.fi
Abstract:
The effects of low-intensity pulsed ultrasound on the mechanical and molecular properties of self-reinforced poly L-lactide (SR-PLLA) screws were studied in vitro. SR-PLLA screws of 4.5 mm diameter were exposed on low-intensity ultrasound for 1, 3. 6, 9, and 12 weeks. After exposure, the bending strength, shear strength, and molecular weight were investigated. There were no differences in the investigated properties between the ultrasound exposure and control groups. We found no evidence that low-intensity ultrasound has any effect on the mechanical or molecular properties of SR-PLLA screws in vitro. The present results suggest that biodegradable SR-PLLA fixation devices are compatible with low-intensity ultrasound in vitro.
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