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Diffuse esophageal leiomyomatosis with localized dense eosinophilic infiltration
C D Morris1, J Wilkinson, D Fox
1Department of Surgery, Hope Hospital, Salford, UK.
Summary
Diffuse esophageal leiomyomatosis, a rare cause of dysphagia, can involve eosinophils and mast cells. Surgical myotomy effectively treated this condition, resolving symptoms for at least three years.
Area of Science:
- Gastroenterology
- Pathology
- Surgical Oncology
Background:
- Diffuse esophageal leiomyomatosis is a rare benign smooth muscle tumor of the esophagus.
- Dysphagia is a common symptom, often associated with chronic inflammation.
Observation:
- This study reports the first case of diffuse esophageal leiomyomatosis with dense eosinophilic and mast cell infiltration.
- The infiltration was specifically localized to the muscularis propria layer of the esophagus.
Findings:
- A long esophageal myotomy was performed as the management strategy.
- The surgical intervention resulted in complete resolution of dysphagia.
Implications:
- This case highlights a unique pathological finding in esophageal leiomyomatosis.
- Long esophageal myotomy is a viable and effective treatment for this rare condition, offering long-term symptom relief.