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Glial choristoma.

P Bajaj1, B S Shubha, K Agarwal

  • 1Department of Pathology, Lady Hardinge Medical College & Kalawati Saran Children's Hospital, New Delhi, India. pramilabajaj@hotmail.com

Indian Journal of Pediatrics
|June 14, 2002
PubMed
Summary
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Glial choristoma, a rare oral cavity malformation, presents as heterotopic central nervous tissue. This case details a newborn

Area of Science:

  • Developmental biology
  • Oral pathology
  • Neuropathology

Background:

  • Glial choristoma is a rare developmental malformation characterized by heterotopic central nervous tissue.
  • Choristomatous lesions in the oral cavity are uncommon, making this a significant finding.

Observation:

  • This report focuses on a glial choristoma originating from the palate of a newborn.
  • The lesion exhibited mature neuroglial tissue, including astrocytes, indicative of developing brain.
  • Cystic spaces lined by cuboidal epithelium, suggesting an ependymal layer, were also observed.

Findings:

  • The glial choristoma was composed primarily of mature neuroglial tissue.
  • Histomorphology revealed astrocytes and ependymal-like structures within the oral lesion.

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  • Limited growth potential is a characteristic feature of this malformation.

    • Implications:

    • Understanding the histomorphology of oral glial choristoma is crucial for diagnosis.
    • This case contributes to the limited literature on glial choristoma in the oral cavity.
    • Further research into associated malformations and clinical features is warranted.