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Updated: Sep 30, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Endovascular treatment for intracranial mycotic aneurysms prior to cardiac surgery
Toshimasa Asai1, Akihiko Usui, Shigeru Miyachi
1Department of Cardiothoracic Surgery, Nagoya University School of Medicine, Nagoya, Japan. asaitm@med.nagoya-u.ac.jp
Abstract:
The management of patients with infective endocarditis complicated by intracranial mycotic aneurysms is controversial. We present the case of a 21-year-old man who suffered from mitral regurgitation with small vegetations due to infective endocarditis. The problem was associated with a ruptured aneurysm on the right anterior cerebral artery and an unruptured aneurysm on the left middle cerebral artery. Endovascular embolization of these aneurysms and subsequent mitral valve repair led to a successful outcome.
Insights
Management of infective endocarditis with intracranial mycotic aneurysms can be challenging. This case study shows successful treatment using endovascular embolization and mitral valve repair for a young patient.
Area of Science:
- Cardiology
- Neurology
- Infectious Diseases
Background:
- Infective endocarditis (IE) poses significant risks, including the development of intracranial mycotic aneurysms.
- The optimal management strategy for IE complicated by these aneurysms remains debated.
- Mitral regurgitation is a common cardiac complication associated with IE.
Observation:
- A 21-year-old male presented with mitral regurgitation and vegetations indicative of IE.
- The patient had a ruptured right anterior cerebral artery aneurysm and an unruptured left middle cerebral artery aneurysm.
- These intracranial aneurysms were directly linked to the infective endocarditis.
Findings:
- Successful endovascular embolization was performed for both the ruptured and unruptured cerebral aneurysms.
- Subsequent mitral valve repair was successfully completed.
- The combined therapeutic approach resulted in a favorable clinical outcome for the patient.
Implications:
- This case highlights the feasibility and success of a combined endovascular and surgical approach for IE with complex intracranial aneurysms.
- Early and aggressive intervention may be crucial for managing life-threatening complications of IE.
- This strategy offers a potential pathway for managing similar complex cases in the future.
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