Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Beating-heart mitral valve surgery: preliminary model and methodology.

Stephen W Downing1, William A Herzog, Joseph S McLaughlin

  • 1Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA. sdowning@smail.umaryland.edu

The Journal of Thoracic and Cardiovascular Surgery
|June 14, 2002
PubMed
Summary

This study demonstrates the feasibility of image-guided mitral valve repair on a beating heart without cardiopulmonary bypass, using echocardiography and endoscopic suturing techniques in a porcine model for future clinical applications.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment of Cutaneous Warts With Multiple Puncture Technique.

Hand (New York, N.Y.)·2018
Same author

Minimally invasive surgery using bipolar radiofrequency energy is effective treatment for refractory atrial fibrillation.

The Annals of thoracic surgery·2012
Same author

Cutaneous warts.

The Journal of hand surgery·2011
Same author

Dynorphin A inhibits NMDA receptors through a pH-dependent mechanism.

Molecular and cellular neurosciences·2003
Same author

Thoracosternotomy for off-pump coronary artery bypass.

The Journal of thoracic and cardiovascular surgery·2003
Same author

What are the risks of using biologic glues?

The Annals of thoracic surgery·2003

Area of Science:

  • Cardiovascular Surgery
  • Medical Imaging
  • Minimally Invasive Procedures

Background:

  • Mitral valve repair traditionally requires cardiopulmonary bypass.
  • Developing off-pump techniques is crucial for reducing surgical risks and improving patient outcomes.

Purpose of the Study:

  • To test the feasibility of image-guided mitral valve repair on a beating heart without cardiopulmonary bypass.
  • To evaluate the accuracy of suturing mitral valve leaflets under echocardiographic guidance.

Main Methods:

  • Developed imaging and suturing techniques in a water bath model.
  • Utilized a porcine model with transesophageal echocardiography for guidance.
  • Employed an endoscopic suturing device to place sutures in the mitral valve leaflets.

Related Experiment Videos

Main Results:

  • Successfully placed sutures in 9 out of 12 attempts with a mean error of 0.8 cm.
  • Identified the short-axis view using an epicardial transesophageal echocardiographic probe as the most effective imaging plane.
  • Observed minimal to moderate air induction without hemodynamic instability or significant arrhythmias.

Conclusions:

  • Image-guided, off-pump mitral valve suturing on a beating heart is achievable.
  • This technique shows promise as a foundation for developing novel off-pump mitral valve repair procedures.