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[Infantile myofibromatosis of the tongue - a case-report]
1Klinik für Hals-Nasen-Ohrenheilkunde, Germany. langer@hno.salvator-kh.de
Insights
This case study details infantile myofibromatosis of the tongue in an infant. Early diagnosis through histology confirmed this rare benign tumor, highlighting the importance of prompt evaluation for oral masses.
Area of Science:
- Pediatric Oncology
- Oral Pathology
Background:
- Infantile myofibromatosis is a rare benign tumor affecting infants.
- Oral cavity involvement, particularly the tongue, is exceptionally uncommon.
Observation:
- A 5-month-old female infant presented with a rapidly growing tongue tumor.
- Histological examination confirmed infantile myofibromatosis.
- The infant's general health remained unaffected throughout the observation period.
Findings:
- Diagnosis of infantile myofibromatosis was established via histological analysis of a biopsy specimen.
- The tumor's rapid growth over four weeks was noted.
- The case represents a rare instance of tongue myofibromatosis in an infant.
Implications:
- This case underscores the importance of considering rare diagnoses in pediatric oral lesions.
- Understanding the different forms of infantile myofibromatosis (solitary, multilocular, generalized) is crucial for prognosis.
- While solitary and multilocular forms often show spontaneous remission, the generalized form carries a high mortality rate due to visceral involvement.
Patient:
We report a case of infantile myofibromatosis of the tongue in a 5 month old female child. The parents reported discovering the tumor in the musculature of the tongue and the tumor had largely grown in size in the space of 4 weeks. The child's health was not impaired at any time. After a specimen was removed for a histological examination, an infantile myofibromatosis was diagnosed.
Discussion:
The occurrence of these tumors in neonates and young children in the oral cavity and in particular in the tongue is rarely reported. Development of the benign tumor disease depends on the form of the tumor, which can be distinguished between a solitaire, a multiloculaire and a generalized form. In contrast to the other two forms, cases of generalized infantile myofibromatosis involve the visceral organs and have a poor prognosis with a mortality rate of 75 %. Spontaneous remission is often reported in the solitaire and multiloculaire varieties of infantile myofibromatosis.
