[Chronic lymphoproliferative disorders]

Chronic lymphoproliferative disorders include several entities that share an initial indolent presentation but are considered at present not to be curable. Follicular lymphoma are more frequent and well characterized; therapeutic recommendations are adapted to prognostic factors such as stage and tumour mass. Marginal zone lymphoma were more recently described and include extranodal MALT lymphomas as well as splenic, leukemic or nodal lymphomas, each with its own clinical features. Lymphocytic lymphomas resemble to chronic lymphocytic leukemia and can be treated in the same way, while mantle cell lymphomas have a very poor outcome. A better definition of these entities should allow to clarify therapeutic recommendations before more efficient treatments become available.