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Growth problems in children with asthma

Ole D Wolthers1

  • 1Children's Clinic Randers, Randers, Denmark. o.d.wolthers@dadlnet.dk

Hormone Research
|June 18, 2002
PubMed

Insights

Children with asthma may experience growth problems, sometimes due to poor asthma control or corticosteroid treatments. Regular height monitoring is crucial for early detection and intervention in pediatric asthma patients.

Area of Science:

  • Pediatric Endocrinology
  • Respiratory Medicine
  • Clinical Pediatrics

Background:

  • Growth problems are a recognized concern in children with asthma.
  • Poorly controlled asthma can rarely lead to significant growth issues.
  • Delayed growth and puberty are observed in some asthmatic boys aged 8-15 years.

Purpose of the Study:

  • To review the impact of asthma and its treatments on pediatric growth.
  • To identify factors influencing growth suppression in asthmatic children.
  • To provide guidelines for monitoring growth in children with asthma.

Main Methods:

  • Literature review on asthma, corticosteroid therapy, and growth.
  • Analysis of growth patterns in asthmatic pediatric populations.
  • Evaluation of corticosteroid dose-response relationships for growth suppression.

Main Results:

  • Systemic corticosteroids consistently suppress growth rate during treatment.
  • Inhaled corticosteroids pose a risk of growth suppression, dependent on dose and delivery device (e.g., budesonide >800 mcg MDI with spacer, >400 mcg DPI; fluticasone propionate >400 mcg DPI).
  • Chronic growth delay and pubertal delay are associated with poor asthma control in some boys.

Conclusions:

  • Asthma management requires careful consideration of potential growth impacts.
  • Regular height monitoring (every 6 months) is essential for all children with asthma.
  • Endocrine evaluation should be guided by general criteria for growth insufficiency.

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