[Genetic aspects of tuberculous infection in adolescents]

Comparative study of the distribution of antigens of HLA-A, B, and C, as well as somato- and phenotype in 234 adolescents has revealed that HLA-A11 and HLA-B12 antigens may indicate a predisposition to tuberculosis and HLA-A28, HLA-B8, and HLA-B51 antigens are involved in its prevention. It has been found that there is predominance of persons having severe forms of somatotype (dolychobrachymorphic) and that there is also a high phenotype stigmatization in adolescents with different manifestations of tuberculous infection.